MELANOMA+4+KS+NK

Vocabulary
 * Fermoral- the bone of the thigh or upper hind limb.
 * Proximal - situated nearer to the center of the body or the point of attachment.
 * Lesion - a region in an organ or tissue that has suffered damage through injury or disease
 * Staging - diagnose or classify (a disease or patient) as having reached a particular stage in the expected progression of the disease.
 * Lymphovascular invasion - Presence or absence of the invasion of the cancer cells into the blood vessels or lymphatic channels.
 * Morphology - the study of the forms of things.
 * Tumor Suppressor Gene Activity - how much the gene that blocks unscheduled cell division
 * Clark Level- a way of seeing how far Melanoma has progressed, by checking the lower layers of skin
 * Breslow Measurement- how thick and advanced the Melanoma is
 * Nevi: multiple nevus, or moles/skin lesions
 * Mitotic Count: Number of cells dividing
 * Picograms: A unit of mass equal to 0.000 000 000 001 grams. Symbol: pg
 * Proto-oncogene- gene that helps to turn normal cells into tumor cells

2. FROM LOOKING AT THE PATHOLOGY REPORT, WHAT INFORMATION DO YOU KNOW? The Patient is female, Lois Becker who was born on December 2, 1964. Lois is freckled, has fair skin, red hair, green eyes, and Caucasian. 18mm X 18mm X 18mm specimen that has an irregular border with a bluish black coloration- received from the patella (knee) of the left leg. The tumor is 6mm X 6mm X 4mm and has been diagnosed as Melanoma. The Melanoma is 4mm into the lower layer of skin, which is Clark level 5. The Melanoma is malignant and at stage 4. 5mm squared cells are currently dividing. The Cancer is in the blood vessels and lymphatic channels. There are 100 picograms There is low tumor suppressor gene activity- (gene isn't working to suppress tumor) The tumor is likely to grow quickly due to high proto-oncogene activity. The mitotic duration is 95%

The Tumor has: - rounded large nucleus - small ER - small golgi The Tumor doesn't have: - cytoskeleton - spindle fibers

3. HOW CAN YOU FIND OUT WHAT THIS INFORMATION MEANS? You can find out what the information means by learning what all the terms mean

4. LIST 5 QUESTIONS YOU WOULD LIKE ANSWERED ABOUT THIS PATHOLOGY. Who creates the pathology report? How bad is this tumor considered? What is the treatment plan for this type of cancer? How long is the life expectancy of the person with this tumor? How many people get this type of cancer?